Title : Quantitative expression analysis of the apoptosis-related genes BCL2, BAX and BCL2L12 in gastric adenocarcinoma cells following treatment with the anticancer drugs cisplatin, etoposide and taxol.

Pub. Date : 2012 Jun

PMID : 22238053






2 Functional Relationships(s)
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1 Treatment of AGS cells with 10 muM cisplatin, 0.5 muM etoposide and 10 nM taxol affected the BCL2, BAX and BCL2L12 mRNA levels, compared to the untreated cells. Paclitaxel BCL2 associated X, apoptosis regulator Homo sapiens
2 Moreover, taxol had an up-regulating effect on both BCL2 and BAX transcript levels after 48 h of incubation. Paclitaxel BCL2 associated X, apoptosis regulator Homo sapiens