Title : Quantitative expression analysis of the apoptosis-related genes BCL2, BAX and BCL2L12 in gastric adenocarcinoma cells following treatment with the anticancer drugs cisplatin, etoposide and taxol.

Pub. Date : 2012 Jun

PMID : 22238053






2 Functional Relationships(s)
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1 Treatment of AGS cells with 10 muM cisplatin, 0.5 muM etoposide and 10 nM taxol affected the BCL2, BAX and BCL2L12 mRNA levels, compared to the untreated cells. Etoposide BCL2 associated X, apoptosis regulator Homo sapiens
2 Cisplatin and etoposide induced a major down-regulation in the BCL2 mRNA levels after 72 h of treatment, while the BAX mRNA levels were slightly up-regulated. Etoposide BCL2 associated X, apoptosis regulator Homo sapiens