Title : Respective roles of CYP2A5 and CYP2F2 in the bioactivation of 3-methylindole in mouse olfactory mucosa and lung: studies using Cyp2a5-null and Cyp2f2-null mouse models.

Pub. Date : 2012 Apr

PMID : 22228748






3 Functional Relationships(s)
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1 Respective roles of CYP2A5 and CYP2F2 in the bioactivation of 3-methylindole in mouse olfactory mucosa and lung: studies using Cyp2a5-null and Cyp2f2-null mouse models. Skatole cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus
2 The aim of this study was to determine whether mouse CYP2A5 and CYP2F2 play critical roles in the bioactivation of 3-methylindole (3MI), a tissue-selective toxicant, in the target tissues, the nasal olfactory mucosa (OM) and lung. Skatole cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus
3 The aim of this study was to determine whether mouse CYP2A5 and CYP2F2 play critical roles in the bioactivation of 3-methylindole (3MI), a tissue-selective toxicant, in the target tissues, the nasal olfactory mucosa (OM) and lung. Skatole cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus