Pub. Date : 2012 Jan
PMID : 22213289
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In p53-null cells, the combination of low dose 5-FU with up to 6 muM quercetin promoted clonogenic survival. | Quercetin | tumor protein p53 | Homo sapiens |
| 2 | Treatment of p53-wild-type cells with 50 muM quercetin reduced drug-induced up-regulation of p53, p21 and BAX. | Quercetin | tumor protein p53 | Homo sapiens |
| 3 | Treatment of p53-wild-type cells with 50 muM quercetin reduced drug-induced up-regulation of p53, p21 and BAX. | Quercetin | tumor protein p53 | Homo sapiens |
| 4 | CONCLUSION: While high doses of quercetin synergize with DNA-damaging agents, the effect of drug combination with quercetin is influenced by the effective doses and the p53 status of the cells. | Quercetin | tumor protein p53 | Homo sapiens |