Pub. Date : 2012 Jan
PMID : 22200605
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Embryonic lethality in mice lacking mismatch-specific thymine DNA glycosylase is partially prevented by DOPS, a precursor of noradrenaline. | Droxidopa | thymine DNA glycosylase | Mus musculus |
| 2 | Consequently, we tested the effect of D, L-threo-3, 4-dihydroxyphenylserine (DOPS), a synthetic precursor of noradrenaline, on the survival of the Tdg (-/-) embryos. | Droxidopa | thymine DNA glycosylase | Mus musculus |
| 3 | DOPS was given to pregnant Tdg (+/-) mice from 6.5 dpc through drinking water. | Droxidopa | thymine DNA glycosylase | Mus musculus |
| 4 | Most of the Tdg (-/-) embryos were alive at 11.5 dpc, and they were partially rescued up to 14.5 dpc by the administration of DOPS. | Droxidopa | thymine DNA glycosylase | Mus musculus |