Title : Pancreatic cancer cells and normal pancreatic duct epithelial cells express an autocrine catecholamine loop that is activated by nicotinic acetylcholine receptors α3, α5, and α7.

Pub. Date : 2012 Feb

PMID : 22188668

1 Functional Relationships(s)
Compound Name
Protein Name
1 The nicotinic agonists acetylcholine, nicotine, and its nitrosated carcinogenic derivative NNK induced the phosphorylation of CREB, ERK, Src, and AKT and these responses were inhibited by propranolol. Nicotine AKT serine/threonine kinase 1 Homo sapiens