Title : Notch signaling modulates hypoxia-induced neuroendocrine differentiation of human prostate cancer cells.

Pub. Date : 2012 Feb

PMID : 22172337






1 Functional Relationships(s)
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1 RESULTS: Exposure of LNCaP cells to low oxygen tension induced a neuroendocrine phenotype, associated with an increased expression of the transcription factor neurogenin3 and neuroendocrine markers, such as neuron-specific enolase, chromogranin A, and beta3-tubulin. Oxygen enolase 2 Homo sapiens