Pub. Date : 2012 Apr 1
PMID : 22171070
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | HSC20 interacts with frataxin and is involved in iron-sulfur cluster biogenesis and iron homeostasis. | Iron | frataxin | Homo sapiens |
| 2 | Friedreich"s ataxia is a neurodegenerative disorder caused by mutations in the frataxin gene that produces a predominantly mitochondrial protein whose primary function appears to be mitochondrial iron-sulfur cluster (ISC) biosynthesis. | Iron | frataxin | Homo sapiens |
| 3 | These results indicate that HSC20 interacts with frataxin structurally and functionally and is important for ISC biogenesis and iron homeostasis in mammals. | Iron | frataxin | Homo sapiens |