Pub. Date : 2012 Apr 1
PMID : 22171070
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | HSC20 interacts with frataxin and is involved in iron-sulfur cluster biogenesis and iron homeostasis. | Iron | HscB mitochondrial iron-sulfur cluster cochaperone | Homo sapiens |
| 2 | HSC20 interacts with frataxin and is involved in iron-sulfur cluster biogenesis and iron homeostasis. | Iron | HscB mitochondrial iron-sulfur cluster cochaperone | Homo sapiens |
| 3 | Knockdown of HSC20 altered cytosolic and mitochondrial iron pools and increased the expression of transferrin receptor 1 and iron regulatory protein 2 consistent with decreased iron bioavailability. | Iron | HscB mitochondrial iron-sulfur cluster cochaperone | Homo sapiens |
| 4 | Knockdown of HSC20 altered cytosolic and mitochondrial iron pools and increased the expression of transferrin receptor 1 and iron regulatory protein 2 consistent with decreased iron bioavailability. | Iron | HscB mitochondrial iron-sulfur cluster cochaperone | Homo sapiens |
| 5 | These results indicate that HSC20 interacts with frataxin structurally and functionally and is important for ISC biogenesis and iron homeostasis in mammals. | Iron | HscB mitochondrial iron-sulfur cluster cochaperone | Homo sapiens |