Title : The roles of prostaglandin EP 1 and 3 receptors in the control of human myometrial contractility.

Pub. Date : 2012 Feb

PMID : 22162473






2 Functional Relationships(s)
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1 Although an EP1 antagonist, ZD6416, had no effect, an EP3 antagonist, L798106, inhibited both spontaneous and PGE(2)-induced contractions. Prostaglandins E prostaglandin E receptor 3 Homo sapiens
2 CONCLUSIONS: EP3 is the primary receptor subtype that mediates PGE(2) induced contractility in human pregnant myometrium at term and represents a possible therapeutic target. Prostaglandins E prostaglandin E receptor 3 Homo sapiens