Title : GM130 gain-of-function induces cell pathology in a model of lysosomal storage disease.

Pub. Date : 2012 Apr 1

PMID : 22156940






2 Functional Relationships(s)
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1 Our previous studies in mucopolysaccharidosis type IIIB (MPSIIIB), a disease in which a genetic defect induces the accumulation of undigested heparan sulfate (HS) fragments, led to the hypothesis that abnormal lysosome formation was related to events occurring at the Golgi level. Heparitin Sulfate N-acetyl-alpha-glucosaminidase Homo sapiens
2 Our previous studies in mucopolysaccharidosis type IIIB (MPSIIIB), a disease in which a genetic defect induces the accumulation of undigested heparan sulfate (HS) fragments, led to the hypothesis that abnormal lysosome formation was related to events occurring at the Golgi level. Heparitin Sulfate N-acetyl-alpha-glucosaminidase Homo sapiens