Title : Bimodal effects of fluoxetine on cerebral nitrergic neurogenic vasodilation in porcine large cerebral arteries.

Pub. Date : 2012 Mar

PMID : 22155207






3 Functional Relationships(s)
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1 In isolated porcine endothelium-denuded basilar arteries in the presence of U-46619-induced active muscle tone, fluoxetine in low concentration (<0.03 muM) significantly enhanced nicotine- and choline-induced relaxations. Nicotine latexin Homo sapiens
2 In addition, fluoxetine at 0.03 muM and 3 muM significantly enhanced and blocked, respectively, nicotine-induced norepinephrine (NE) release from cerebral perivascular sympathetic nerves. Nicotine latexin Homo sapiens
3 In addition, fluoxetine at 0.03 muM and 3 muM significantly enhanced and blocked, respectively, nicotine-induced norepinephrine (NE) release from cerebral perivascular sympathetic nerves. Nicotine latexin Homo sapiens