Title : Inhibitors of testosterone biosynthetic and metabolic activation enzymes.

Pub. Date : 2011 Dec 2

PMID : 22138857






1 Functional Relationships(s)
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1 Testosterone is also metabolically activated into more potent androgen dihydrotestosterone by two isoforms 5alpha-reductase 1 (SRD5A1) and 2 (SRD5A2) in Leydig cells and peripheral tissues. Dihydrotestosterone 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Cricetulus griseus