Title : CYP2C76 non-synonymous variants in cynomolgus and rhesus macaques.

Pub. Date : 2012

PMID : 22123125






2 Functional Relationships(s)
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1 Molecular modeling indicated that the reduced catalytic activity of the L65F variant in progesterone 16alpha-hydroxylation possibly resulted from a longer distance of progesterone to the heme in the active site of the CYP2C76 protein. Progesterone cytochrome P450 family 2 subfamily C member 76 Macaca fascicularis
2 Molecular modeling indicated that the reduced catalytic activity of the L65F variant in progesterone 16alpha-hydroxylation possibly resulted from a longer distance of progesterone to the heme in the active site of the CYP2C76 protein. Progesterone cytochrome P450 family 2 subfamily C member 76 Macaca fascicularis