Pub. Date : 2012 Jan
PMID : 22120617
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Low arsenite concentrations induce cell proliferation via activation of VEGF signaling in human neuroblastoma SH-SY5Y cells. | arsenite | vascular endothelial growth factor A | Homo sapiens |
| 2 | Inhibition of VEGF-induced signaling by SU4312, the inhibitor of VEGF receptor 2 kinase, and by treatment with anti-VEGF antibody blocked arsenite-induced increases in cell proliferation. | arsenite | vascular endothelial growth factor A | Homo sapiens |
| 3 | Inhibition of VEGF-induced signaling by SU4312, the inhibitor of VEGF receptor 2 kinase, and by treatment with anti-VEGF antibody blocked arsenite-induced increases in cell proliferation. | arsenite | vascular endothelial growth factor A | Homo sapiens |
| 4 | Inhibition of VEGF-induced signaling by SU4312, the inhibitor of VEGF receptor 2 kinase, and by treatment with anti-VEGF antibody blocked arsenite-induced increases in cell proliferation. | arsenite | vascular endothelial growth factor A | Homo sapiens |
| 5 | Moreover, arsenite caused activation of ERK, a key signaling molecule involved in cell proliferation, and this activation was attenuated by SU4312, suggesting that ERK activation contributes to VEGF-mediated cell proliferation induced by arsenite. | arsenite | vascular endothelial growth factor A | Homo sapiens |
| 6 | Moreover, arsenite caused activation of ERK, a key signaling molecule involved in cell proliferation, and this activation was attenuated by SU4312, suggesting that ERK activation contributes to VEGF-mediated cell proliferation induced by arsenite. | arsenite | vascular endothelial growth factor A | Homo sapiens |