Pub. Date : 1990 Jul-Aug
PMID : 2211341
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tumor necrosis factor and interleukin-1 stimulate testosterone secretion in adult male rat Leydig cells in vitro. | Testosterone | tumor necrosis factor-like | Rattus norvegicus |
| 2 | The actions of two cytokines, tumor necrosis factor (TNF) and interleukin-1 (IL-1), on testosterone production by dispersed adult testis cells and purified Leydig cells in culture were studied. | Testosterone | tumor necrosis factor-like | Rattus norvegicus |
| 3 | Both TNF and IL-1 stimulated basal secretion of testosterone in whole testis cells, as well as purified Leydig cells. | Testosterone | tumor necrosis factor-like | Rattus norvegicus |
| 4 | Additionally, both TNF and IL-1 augmented maximally hCG stimulated testosterone secretion. | Testosterone | tumor necrosis factor-like | Rattus norvegicus |
| 5 | We have concluded from this data that TNF and IL-1 stimulate the testosterone secretion by adult rat Leydig cells. | Testosterone | tumor necrosis factor-like | Rattus norvegicus |