Pub. Date : 2012 Jan
PMID : 22111602
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CYP2B6 516G>T (non-wild-type/wild-type) correlated with nevirapine pharmacokinetic parameters; geometric mean ratios (95% CI): 1.75 (1.27-2.40) for area under the concentration time curve (AUC)(0-12 h), 1.58 (1.03-2.42) for C(0), and 0.53 (0.31-0.91) for clearance. | Nevirapine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 2 | The T allele for CYP2B6 516 was significantly associated with nevirapine exposure. | Nevirapine | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |