Title : Nicotine induces fibrogenic changes in human liver via nicotinic acetylcholine receptors expressed on hepatic stellate cells.

Pub. Date : 2012 Jan 6

PMID : 22108052






1 Functional Relationships(s)
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1 Nicotine induction of hHSC proliferation, upregulation of collagen1-alpha2 and the pro-fibrogenic cytokine transforming growth factor beta 1 (TGF-beta1) was determined along with involved intracellular signaling pathways. Nicotine UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens