Title : Circadian clock protein BMAL1 regulates cellular senescence in vivo.

Pub. Date : 2011 Dec 1

PMID : 22101268






6 Functional Relationships(s)
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Protein Name
Organism
1 Increased sensitivity of Bmal1(-/-) cells to oxidative stress was p53 independent and correlated with the disrupted regulation of reactive oxygen species (ROS) homeostasis in BMAL1 deficient cells: indeed, circadian oscillations of ROS level can be induced in wild-type but not in Bmal1(-/-) cells. Reactive Oxygen Species aryl hydrocarbon receptor nuclear translocator-like Mus musculus
2 Increased sensitivity of Bmal1(-/-) cells to oxidative stress was p53 independent and correlated with the disrupted regulation of reactive oxygen species (ROS) homeostasis in BMAL1 deficient cells: indeed, circadian oscillations of ROS level can be induced in wild-type but not in Bmal1(-/-) cells. Reactive Oxygen Species aryl hydrocarbon receptor nuclear translocator-like Mus musculus
3 Increased sensitivity of Bmal1(-/-) cells to oxidative stress was p53 independent and correlated with the disrupted regulation of reactive oxygen species (ROS) homeostasis in BMAL1 deficient cells: indeed, circadian oscillations of ROS level can be induced in wild-type but not in Bmal1(-/-) cells. Reactive Oxygen Species aryl hydrocarbon receptor nuclear translocator-like Mus musculus
4 Increased sensitivity of Bmal1(-/-) cells to oxidative stress was p53 independent and correlated with the disrupted regulation of reactive oxygen species (ROS) homeostasis in BMAL1 deficient cells: indeed, circadian oscillations of ROS level can be induced in wild-type but not in Bmal1(-/-) cells. Reactive Oxygen Species aryl hydrocarbon receptor nuclear translocator-like Mus musculus
5 Increased sensitivity of Bmal1(-/-) cells to oxidative stress was p53 independent and correlated with the disrupted regulation of reactive oxygen species (ROS) homeostasis in BMAL1 deficient cells: indeed, circadian oscillations of ROS level can be induced in wild-type but not in Bmal1(-/-) cells. Reactive Oxygen Species aryl hydrocarbon receptor nuclear translocator-like Mus musculus
6 Increased sensitivity of Bmal1(-/-) cells to oxidative stress was p53 independent and correlated with the disrupted regulation of reactive oxygen species (ROS) homeostasis in BMAL1 deficient cells: indeed, circadian oscillations of ROS level can be induced in wild-type but not in Bmal1(-/-) cells. Reactive Oxygen Species aryl hydrocarbon receptor nuclear translocator-like Mus musculus