Title : Prepubertal daidzein exposure enhances mammary gland differentiation and regulates the expression of estrogen receptor-alpha and apoptotic proteins.

Pub. Date : 2011

PMID : 22091435






3 Functional Relationships(s)
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1 Prepubertal daidzein exposure enhances mammary gland differentiation and regulates the expression of estrogen receptor-alpha and apoptotic proteins. daidzein estrogen receptor 1 Homo sapiens
2 Mechanism of chemoprevention by daidzein (500 mug/g bwt) was examined by injecting it subcutaneously at 16th, 18th, and 20th day postpartum, followed by counting of terminal end buds (TEBs), terminal ducts (TDs), and lobules and immunohistochemistry of ER-alpha, Bcl2, Bax, and caspase-3. daidzein estrogen receptor 1 Homo sapiens
3 There was a significant decrease of ER-alpha expression at PND21 and increase in its expression at PND50, in daidzein-treated animals. daidzein estrogen receptor 1 Homo sapiens