Title : Oxidation of CaMKII determines the cardiotoxic effects of aldosterone.

Pub. Date : 2011 Nov 13

PMID : 22081025






1 Functional Relationships(s)
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1 Myocardial CaMKII inhibition, overexpression of methionine sulfoxide reductase A (an enzyme that reduces oxidized CaMKII) or NADPH oxidase deficiency prevented aldosterone-enhanced cardiac rupture after myocardial infarction. Aldosterone methionine sulfoxide reductase A Mus musculus