Title : Induction of oxidative stress and inhibition of superoxide dismutase expression in rat cerebral cortex and cerebellum by PTU-induced hypothyroidism and its reversal by curcumin.

Pub. Date : 2012 Aug

PMID : 22076484






2 Functional Relationships(s)
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1 The decreased translated products (SOD1 and SOD2) and the unchanged activity of SOD in cerebral cortex of PTU-treated rats were increased on supplementation of curcumin to the hypothyroid rats. Propylthiouracil superoxide dismutase 2 Rattus norvegicus
2 Declined translated products of SOD1 and SOD2 in cerebellum of PTU-treated rats were alleviated on administration of curcumin to hypothyroid rats. Propylthiouracil superoxide dismutase 2 Rattus norvegicus