Title : Enzyme replacement therapy with idursulfase for mucopolysaccharidosis type II (Hunter syndrome).

Pub. Date : 2011 Nov 9

PMID : 22071845






2 Functional Relationships(s)
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1 BACKGROUND: Mucopolysaccharidosis II, also known as Hunter syndrome, is a rare, X-linked disease caused by a deficiency of the lysosomal enzyme iduronate-2-sulfatase, which catalyses a step in the catabolism of glycosaminoglycans. Glycosaminoglycans iduronate 2-sulfatase Homo sapiens
2 Idursulfase antibodies were detected in 31.7% of patients at the end of the study and they were related to a smaller reduction in urine glycosaminoglycan levels. Glycosaminoglycans iduronate 2-sulfatase Homo sapiens