Title : Lovastatin and simvastatin prevention studies.

Pub. Date : 1990 Sep 18

PMID : 2206035






1 Functional Relationships(s)
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1 These drugs, including lovastatin and simvastatin, competitively inhibit 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of intracellular cholesterol synthesis. Simvastatin 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens