Title : Tianeptine potentiates AMPA receptors by activating CaMKII and PKA via the p38, p42/44 MAPK and JNK pathways.

Pub. Date : 2011 Dec

PMID : 22056552






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Tianeptine, 10 muM, enhanced the GluA1-dependent initial phase of LTP, whereas 100 muM impaired the latter phases, indicating a critical role of GluA1 subunit phosphorylation in the excitation. tianeptine glutamate receptor, ionotropic, AMPA1 (alpha 1) Mus musculus
2 Tianeptine, 10 muM, enhanced the GluA1-dependent initial phase of LTP, whereas 100 muM impaired the latter phases, indicating a critical role of GluA1 subunit phosphorylation in the excitation. tianeptine glutamate receptor, ionotropic, AMPA1 (alpha 1) Mus musculus
3 Tianeptine rapidly increased the phosphorylation level of Ser(831)-GluA1 and Ser(845)-GluA1. tianeptine glutamate receptor, ionotropic, AMPA1 (alpha 1) Mus musculus
4 Tianeptine rapidly increased the phosphorylation level of Ser(831)-GluA1 and Ser(845)-GluA1. tianeptine glutamate receptor, ionotropic, AMPA1 (alpha 1) Mus musculus