Title : Development of multiplex PCR method for the analysis of glutathione s-transferase polymorphism.

Pub. Date : 2011 Oct 1

PMID : 22047155






7 Functional Relationships(s)
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1 Genetic polymorphisms of glutathione S-transferase (GST), which is involved in the metabolism of busulfan, have been implicated in interindividual variability in busulfan pharmacokinetics. Busulfan glutathione S-transferase kappa 1 Homo sapiens
2 Genetic polymorphisms of glutathione S-transferase (GST), which is involved in the metabolism of busulfan, have been implicated in interindividual variability in busulfan pharmacokinetics. Busulfan glutathione S-transferase kappa 1 Homo sapiens
3 Genetic polymorphisms of glutathione S-transferase (GST), which is involved in the metabolism of busulfan, have been implicated in interindividual variability in busulfan pharmacokinetics. Busulfan glutathione S-transferase kappa 1 Homo sapiens
4 Genetic polymorphisms of glutathione S-transferase (GST), which is involved in the metabolism of busulfan, have been implicated in interindividual variability in busulfan pharmacokinetics. Busulfan glutathione S-transferase kappa 1 Homo sapiens
5 Development of a rapid and simplified method for polygenic analysis of GST may facilitate large pharmacogenetic studies and clinical application of individualized busulfan dose adjustment. Busulfan glutathione S-transferase kappa 1 Homo sapiens
6 OBJECTIVE: The aim of this study was to extend the application of the TotalPlex method to the specific GST gene families (A1, P1, M1, and T1) that are related to busulfan metabolism, and thereby facilitate pharmacogenetic analysis of GST polymorphisms. Busulfan glutathione S-transferase kappa 1 Homo sapiens
7 OBJECTIVE: The aim of this study was to extend the application of the TotalPlex method to the specific GST gene families (A1, P1, M1, and T1) that are related to busulfan metabolism, and thereby facilitate pharmacogenetic analysis of GST polymorphisms. Busulfan glutathione S-transferase kappa 1 Homo sapiens