Title : Protein-tyrosine phosphatase 1B modulates early endosome fusion and trafficking of Met and epidermal growth factor receptors.

Pub. Date : 2011 Dec 30

PMID : 22045810






1 Functional Relationships(s)
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1 Here, we demonstrate that knockdown of PTP1B or expression of a PTP1B trapping aspartic acid-to-alanine substitution (D/A) mutant delayed ligand-induced degradation of the Met and EGF RTKs. Aspartic Acid protein tyrosine phosphatase non-receptor type 1 Homo sapiens