Title : The role of substance P in depression: therapeutic implications.

Pub. Date : 2002 Mar

PMID : 22033776






1 Functional Relationships(s)
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1 A double-blind study of MK869, a selective NK1 receptor antagonist that blocks the action of substance P, showed significant activity versus placebo and fewer sexual side effects than paroxetine in outpatients with major depression and moderate anxiety. Paroxetine tachykinin precursor 1 Homo sapiens