Title : Curcumin and enalapril ameliorate renal failure by antagonizing inflammation in 5/6 nephrectomized rats: role of phospholipase and cyclooxygenase.

Pub. Date : 2012 Feb 15

PMID : 22031851






2 Functional Relationships(s)
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1 We hypothesized that curcumin, by blocking the inflammatory mediators TNF-alpha and IL-1beta, could also reduce cyclooxygenase (COX) and phospholipase expression in the kidney. Curcumin interleukin 1 beta Rattus norvegicus
2 Compared with controls, Nx animals had higher plasma/kidney TNF-alpha and IL-1beta, which were reduced by curcumin and enalapril treatment. Curcumin interleukin 1 beta Rattus norvegicus