Title : Inhibition of cytochrome P450 enzymes involved in ketamine metabolism by use of liver microsomes and specific cytochrome P450 enzymes from horses, dogs, and humans.

Pub. Date : 2011 Nov

PMID : 22023129






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 For all 3 species, inhibitors of CYP3A4, CYP2A6, CYP2C19, CYP2B6, and CYP2C9 diminished N-demethylation of ketamine. Nitrogen cytochrome P450 family 2 subfamily A member 6 Homo sapiens