Title : Elevated global SUMOylation in Ubc9 transgenic mice protects their brains against focal cerebral ischemic damage.

Pub. Date : 2011

PMID : 22016779






1 Functional Relationships(s)
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1 We have previously shown that a massive increase in global SUMOylation occurs during torpor in ground squirrels, and that overexpression of Ubc9 and/or SUMO-1 in cell lines and cortical neurons protects against oxygen and glucose deprivation. Oxygen ubiquitin-conjugating enzyme E2I Mus musculus