Title : Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3.

Pub. Date : 2011

PMID : 22016776






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-alpha/VEGF/Rho-GTPases: pivotal role of STAT-3. benzyl isothiocyanate vascular endothelial growth factor A Homo sapiens
2 Immunoblotting of BITC treated tumors show reduced expression of STAT-3 phosphorylation (Tyr-705), HIF-alpha, VEGFR-2, VEGF, MMP-2, CD31 and RhoC. benzyl isothiocyanate vascular endothelial growth factor A Homo sapiens