Title : Hepatic ABCA1 and VLDL triglyceride production.

Pub. Date : 2012 May

PMID : 22001232






2 Functional Relationships(s)
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1 Individuals with Tangier disease also have elevated plasma TG concentrations and a near absence of HDL, resulting from mutations in ATP binding cassette transporter A1 (ABCA1), which facilitates the efflux of cellular phospholipid and free cholesterol to assemble with apolipoprotein A-I (apoA-I), forming nascent HDL particles. Cholesterol ATP binding cassette subfamily A member 1 Rattus norvegicus
2 Individuals with Tangier disease also have elevated plasma TG concentrations and a near absence of HDL, resulting from mutations in ATP binding cassette transporter A1 (ABCA1), which facilitates the efflux of cellular phospholipid and free cholesterol to assemble with apolipoprotein A-I (apoA-I), forming nascent HDL particles. Cholesterol ATP binding cassette subfamily A member 1 Rattus norvegicus