Title : Parthenolide inhibits ERK and AP-1 which are dysregulated and contribute to excessive IL-8 expression and secretion in cystic fibrosis cells.

Pub. Date : 2011 Oct 12

PMID : 21992677






1 Functional Relationships(s)
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1 Using a luciferase promoter assay, our studies showed that parthenolide decreased activation of the IL-8 promoter in CF cells stimulated with TNFalpha/IL-1beta. parthenolide interleukin 1 beta Homo sapiens