Title : Oxidative mechanisms for the biotransformation of 1-methyl-1,6-dihydropyridine-2-carbaldoxime to pralidoxime chloride.

Pub. Date : 2011 Dec 19

PMID : 21989207






2 Functional Relationships(s)
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1 AIMS: Due to pralidoxime chloride"s (2-PAM) positive charge, it"s penetration through the blood brain barrier (BBB) and reactivation of organophosphate (OP) inhibited central nervous system (CNS) acetylcholinesterase (AChE) is poor. pralidoxime acetylcholinesterase Cavia porcellus
2 AIMS: Due to pralidoxime chloride"s (2-PAM) positive charge, it"s penetration through the blood brain barrier (BBB) and reactivation of organophosphate (OP) inhibited central nervous system (CNS) acetylcholinesterase (AChE) is poor. pralidoxime acetylcholinesterase Cavia porcellus