Pub. Date : 2012 Jan 1
PMID : 21956166
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Using pharmacological inhibitors, we observed that carbachol inhibits oxalate transport through the M(3) muscarinic receptor and phospholipase C. Utilizing the Src inhibitor PP2 and phosphorylation studies, we found that the observed regulation downstream of PKC-delta is partially mediated by c-Src. | Oxalates | cholinergic receptor muscarinic 3 | Homo sapiens |
| 2 | We conclude that carbachol negatively regulates oxalate transport by reducing SLC26A6 surface expression in T84 cells through signaling pathways including the M(3) muscarinic receptor, phospholipase C, PKC-delta, and c-Src. | Oxalates | cholinergic receptor muscarinic 3 | Homo sapiens |