Title : The activation of the p53 pathway by the AMP mimetic AICAR is reduced by inhibitors of the ATM or mTOR kinases.

Pub. Date : 2011 Nov-Dec

PMID : 21945951






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A reduced supply of energy at the cellular level leads to an increased concentration of AMP, which, in turn, results in LKB1-mediated activation of the AMPK kinase. Adenosine Monophosphate serine/threonine kinase 11 Homo sapiens