Title : Analysis of binding site hot spots on the surface of Ras GTPase.

Pub. Date : 2011 Nov 4

PMID : 21945529






1 Functional Relationships(s)
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1 Here, we use a combination of multiple solvent crystal structures and computational solvent mapping (FTMap) to determine binding site hot spots in the "off" and "on" allosteric states of the GTP-bound form of H-Ras. Guanosine Triphosphate HRas proto-oncogene, GTPase Homo sapiens