Title : L-Proline/CoCl2-catalyzed highly diastereo- and enantioselective direct aldol reactions.

Pub. Date : 2011 Sep 19

PMID : 21932236






1 Functional Relationships(s)
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1 Excellent yields (up to 93%) and a significant improvement in diastereoselectivity (anti/syn up to 45:1) as well as enantioselectivity (up to more than 99% ee) compared with using proline as the sole catalyst were observed. Proline synemin Homo sapiens