Title : Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease.

Pub. Date : 2011

PMID : 21918687






1 Functional Relationships(s)
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1 Mechanistic analyses indicated that pre-pathology treatment with APalpha increased expression of liver-X-receptor, pregnane-X-receptor, and 3-hydroxy-3-methyl-glutaryl-CoA-reductase (HMG-CoA-R), three proteins that regulate cholesterol homeostasis and clearance from brain. Cholesterol glutamyl aminopeptidase Mus musculus