Pub. Date : 2011 Nov
PMID : 21903868
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Squalene synthase (SQS) utilizes FPP in the first committed step from the mevalonate pathway toward cholesterol biosynthesis. | Cholesterol | farnesyl-diphosphate farnesyltransferase 1 | Homo sapiens |
| 2 | Squalene synthase (SQS) utilizes FPP in the first committed step from the mevalonate pathway toward cholesterol biosynthesis. | Cholesterol | farnesyl-diphosphate farnesyltransferase 1 | Homo sapiens |
| 3 | The combination of an SQS inhibitor with an HMGCR or FDPS inhibitor provides a rational approach for reducing cholesterol synthesis while preventing nonsterol isoprenoid depletion. | Cholesterol | farnesyl-diphosphate farnesyltransferase 1 | Homo sapiens |