Pub. Date : 2011 Oct
PMID : 21882049
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study the effect of spermidine (Spd), spermine (Spm), and glycerol on glycation, structure and function of lysozyme (LZ), as an extra-cellular protein, by different techniques is investigated. | Glycerol | lysozyme | Homo sapiens |
| 2 | In this study the effect of spermidine (Spd), spermine (Spm), and glycerol on glycation, structure and function of lysozyme (LZ), as an extra-cellular protein, by different techniques is investigated. | Glycerol | lysozyme | Homo sapiens |
| 3 | LZ is incubated with or without glucose (50 or 100 mM) in the absence or presence of Spd/Spm/glycerol at 37 C up to 16 weeks. | Glycerol | lysozyme | Homo sapiens |
| 4 | In contrast, glycerol inhibits the LZ glycation and prevents the large changes on its structure and function. | Glycerol | lysozyme | Homo sapiens |
| 5 | Polyamines also directly bind to LZ, increase its positive charges and hence induce more glycation; more conformational changes, oligomerization and its inactivation in the presence of glucose, but glycerol affect the protein environment and preserve protein from these harmful effects. | Glycerol | lysozyme | Homo sapiens |