Title : TC-PTP dephosphorylates the guanine nucleotide exchange factor C3G (RapGEF1) and negatively regulates differentiation of human neuroblastoma cells.

Pub. Date : 2011

PMID : 21876762






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 C3G is regulated by tyrosine phosphorylation on Y504, known to be mediated by c-Abl and Src family kinases. Tyrosine Rap guanine nucleotide exchange factor 1 Homo sapiens
2 TC48 expression inhibited forskolin induced tyrosine phosphorylation of C3G and neurite outgrowth in IMR-32 cells. Tyrosine Rap guanine nucleotide exchange factor 1 Homo sapiens