Title : Fluorogenic cephalosporin substrates for β-lactamase TEM-1.

Pub. Date : 2011 Dec 1

PMID : 21867672






1 Functional Relationships(s)
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1 Cephalosporin was used to synthesize soluble and precipitating fluorogenic beta-lactam substrates that demonstrated differential catalytic hydrolysis by three different subtypes of beta-lactamase: TEM-1 (class A), p99 (class C), and a Bacillus cereus enzyme sold by Genzyme (class B). beta-Lactams CD248 molecule Homo sapiens