Title : In vitro and in vivo small intestinal metabolism of CYP3A and UGT substrates in preclinical animals species and humans: species differences.

Pub. Date : 2011 Nov

PMID : 21859377






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Intestinal first-pass metabolism has a great impact on the bioavailability of cytochrome P450 3A4 (CYP3A) and/or uridine 5"-diphosphate (UDP)-glucoronosyltranferase (UGT) substrates in humans. Uridine Diphosphate UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens
2 Intestinal first-pass metabolism has a great impact on the bioavailability of cytochrome P450 3A4 (CYP3A) and/or uridine 5"-diphosphate (UDP)-glucoronosyltranferase (UGT) substrates in humans. Uridine Diphosphate UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens