Pub. Date : 2011 Oct 3
PMID : 21851097
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we used novel strategies to target microsomal glutathione transferase 1 (MGST1) and glutathione transferase pi (GSTP) that are often overexpressed in tumors and confer resistance against a number of cytostatic drugs, including cisplatin and doxorubicin (DOX). | Cisplatin | microsomal glutathione S-transferase 1 | Homo sapiens |
| 2 | Here we show that ethacraplatin is easily taken up by the cells and can reverse cisplatin resistance in MGST1 overexpressing MCF7 cells. | Cisplatin | microsomal glutathione S-transferase 1 | Homo sapiens |