Pub. Date : 2011 Oct 21
PMID : 21847495
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our previous studies identified two 2-benzoylaminobenzoate derivatives 1, which potently inhibited superoxide (O(2) (-)) generation induced by formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP) in human neutrophils. | Superoxides | formyl peptide receptor 1 | Homo sapiens |
| 2 | Our previous studies identified two 2-benzoylaminobenzoate derivatives 1, which potently inhibited superoxide (O(2) (-)) generation induced by formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP) in human neutrophils. | Superoxides | formyl peptide receptor 1 | Homo sapiens |
| 3 | Of these, compounds 17, 18, 46, 49, and 50 showed the most potent inhibitory effect on FMLP-induced release of O(2) (-) in human neutrophils with IC(50) values of 0.20, 0.16, 0.15, 0.06, and 0.29 muM, respectively. | Superoxides | formyl peptide receptor 1 | Homo sapiens |