Title : Strategies for optimization of short-term genotoxicity tests: the synergistic effect of NADPH and NADH on P450 function in processing pre-mutagens.

Pub. Date : 1990 Jan

PMID : 2184312






1 Functional Relationships(s)
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1 Mutagenesis experiments using TTCE in the diploid D7 strain of Saccharomyces cerevisiae (from stationary growth phase) as a biological test system, showed a significant enhancement of mitotic gene conversion and reverse point mutation frequencies when using NADPH plus NADH in the medium. NAD 2,4-dienoyl CoA reductase 1, mitochondrial Mus musculus