Pub. Date : 2011 Nov
PMID : 21825115
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recently, progesterone receptor membrane component 1 (PGRMC1), which shares a key structural motif with cytochrome b(5), has been reported to bind to sterol- or steroid-synthesizing P450s, enhancing their activities. | Steroids | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 2 | In conclusion, in contrast to sterol- or steroid-synthesizing P450s, we found that PGRMC1 negatively modulates the human drug-metabolizing activities of P450 through direct interaction. | Steroids | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 3 | In conclusion, in contrast to sterol- or steroid-synthesizing P450s, we found that PGRMC1 negatively modulates the human drug-metabolizing activities of P450 through direct interaction. | Steroids | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |