Title : Effects of androgen and leptin on behavioral and cellular responses in female rats.

Pub. Date : 2011 Sep

PMID : 21819988






2 Functional Relationships(s)
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1 One week of DHT exposure decreased androgen receptor (AR) expression in the hypothalamus and leptin synthesis and function in adipocytes; it also inhibited signal transducer and activator of transcription 3 (STAT3) and attenuated leptin activity by increasing levels of soluble leptin receptor, a leptin-binding protein, in the hypothalamus. Dihydrotestosterone androgen receptor Rattus norvegicus
2 One week of DHT exposure decreased androgen receptor (AR) expression in the hypothalamus and leptin synthesis and function in adipocytes; it also inhibited signal transducer and activator of transcription 3 (STAT3) and attenuated leptin activity by increasing levels of soluble leptin receptor, a leptin-binding protein, in the hypothalamus. Dihydrotestosterone androgen receptor Rattus norvegicus